Experimental model of ultrasound thermotherapy in rats inoculated with Walker-236 tumor

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[Experimental model of ultrasound thermotherapy in rats inoculated with Walker-236 tumor].

PURPOSE To develop a model to evaluate the effects of focal pulsed ultrasound (US) waves as a source of heat for treatment of murine subcutaneous implanted Walker tumor. METHODS An experimental, controlled, comparative study was conducted. Twenty male Wistar rats (160-300 g) randomized in 2 equal groups (G-1: Control and G-2: Hyperthermia) were inoculated with Walker-256 carcinosarcoma tumor....

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The oophorectomy effect on Walker 256 tumor inoculated into the vagina and uterine cervix of female rats.

PURPOSE Verify the effect of oophorectomy on the evolution of the Walker 256 tumor inoculated into the vagina and cervix of female rats. METHODS Ten Wistar, female rats were used, distributed into two groups with 05 animals each: Tumor group (TG): Rats inoculated with Walker 256 tumor; Oophorectomy group (OG): oophorectomized rats inoculated with Walker 256 tumor. The day before the tumor vag...

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Blockade of Hypoxia: The Impact on Tumor Growth in an Experimental Tumor Model

Background: Tumor microenvironment is an active factor participating in immunoregulation, thereby preventing immunosurveillance and limiting the efficacy of anticancer therapies. Hypoxia as a major characteristic of solid tumors causes the expression of Hypoxia-Inducible Factor-1α (HIF-1α). This is a transcription factor that mediates hypoxic responses of tumor cells and involves in the express...

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Serum polysaccharide levels in rats bearing the Walker 256 tumor.

Previous work on human subjects (9) has shown that the polysaccharide associated with serum proteins is significantly elevated in malig nancy. Little is known concerning the correlation between this elevation and the cancerous condi tion. Work in this laboratory has shown that the serum polysaccharide of dogs is increased in sev eral types of experimental inflammation (7). An elevation also occ...

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Experimental inoculation model of Walker 256 carcinoma into vagina and cervix uteri of female rats.

PURPOSE To establish an inoculation model of Walker 256 carcinoma on cervix uteri and vagina of rats. METHODS Fifteen female rats were used, and assigned to three groups each one with five rats: group A - rats with 4 x 10(6) cells of Walker 256 carcinoma without acid acetic inoculation; group B - rats with 2 x 10(6) cells of Walker 256 carcinoma with acid acetic inoculation and group C: rats ...

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ژورنال

عنوان ژورنال: Acta Cirurgica Brasileira

سال: 2011

ISSN: 0102-8650

DOI: 10.1590/s0102-86502011000700011